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KMID : 0882419930450030383
Korean Journal of Medicine
1993 Volume.45 No. 3 p.383 ~ p.387
A Case of Angioimmunoblastic Lymphadenopathy Presenting as Polyarthritis
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Abstract
ngioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a lymphoproliferative
disorder with characteristic clinical features and lymph node histology. Arthritis is a
uncommon clinical finding of AILD. We described a patient with AILD whose initial
presentation was a symmetrical polyarthritis. Radiograph of involved joints revealed soft
tissue swelling and periarticular osteoporosis without bony erosions. Lymph node biopsy
showed characteristic findings.The patient was treated with systemic chemotherapy with
C-MOPP regimen and showed partial remission.
Since prognosis is greatly altered and treatment with high dose steroid or cytotoxic agents
is indicated, AILD should be considered as a diagnostic possibility in patients with apparent
systemic connective tissue disease in whom marked lymphadenopathy, weight loss, or steady
deterioration developed.
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